Backed by a dramatic cover of Coldplay’s “Don’t Panic” (from singer Charity), the new trailer for Bryan Singer’s X-Men: Apocalypse has arrived with four horsemen in tow.

Focused on the world-destroying villain, the globe’s first mutant, Apocalypse teases the end of humanity and maybe even an X-Men member or two.

“Forget everything you think you know,” Jennifer Lawrence’s Mystique tells the young students of Charles Xavier’s School for Gifted Youngsters. “You’re not students anymore; you’re X-Men.” Moments later, Apocalypse (Oscar Isaac) is choking the life out of her.